Thermo Fisher Scientific Insulin/Proinsulin Monoclonal Antibody (D3E7cc)
Insulin 및 Proinsulin 검출용 Mouse monoclonal antibody (Clone D3E7cc). IHC(F) 및 ELISA에 적합하며, 다양한 종(Bovine, Human, Pig, Rat)에 반응. Protein A로 정제된 액상 시약으로 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- MA116710
- 판매단위
- pk
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-Dependent
ELISA
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Pig, Rat |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D3E7cc |
| Immunogen | Hybridoma clone derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with native human insulin. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 7.2 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568588 |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) covalently linked via two disulfide bonds and one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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