Thermo Fisher Scientific ELOVL6 Polyclonal Antibody
ELOVL6 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 Immunocytochemistry에 적합하며, Affinity chromatography로 정제된 액상 항체입니다. 지방산 합성 관련 연구에 활용 가능합니다.
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- PA5106662
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ELOVL6 (Accession Q9H5J4), corresponding to amino acid residues N29–L79 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854330 |
Product Specific Information
Antibody detects endogenous levels of total ELOVL6.
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of the fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and is a target of SREBP-1.
It plays an important role in de novo synthesis of long-chain saturated and monounsaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase.
ELOVL6 is predicted to influence tissue fatty acid composition, and inhibition of this elongase may represent a therapeutic approach for improving insulin resistance, diabetes, and cardiovascular risks, even under conditions of obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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