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Thermo Fisher Scientific mGluR3 Polyclonal Antibody
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Thermo Fisher Scientific mGluR3 Polyclonal Antibody

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Rabbit polyclonal antibody targeting human mGluR3. Validated for WB, IHC(P), and ICC/IF. High specificity using synthetic peptide immunogen. Supplied as liquid, 1 mg/mL in PBS with 0.1% sodium azide. Suitable for research use only.

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pk
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Thermo Fisher Scientific PA120578 mGluR3 Polyclonal Antibody 25 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific mGluR3 Polyclonal Antibody

Applications

Application Tested Dilution
Western Blot (WB) Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P)) 9 µg/mL
Immunocytochemistry (ICC/IF) Assay-dependent

Product Specifications

Specification Details
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS
Contains 0.1% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_560073

Product Specific Information

PA1-20578 detects Metabotropic Glutamate Receptor 3 (mGluR3) in human samples.

Target Information

Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors involved in fast excitatory synaptic transmission.
Metabotropic glutamate receptors (mGluRs) regulate enzymes producing second messengers via G-protein coupling.

  • Group I receptors (mGluR1a, mGluR5): stimulate phospholipase C, increasing phosphoinositide turnover and calcium release.
  • Group II and III receptors (including mGluR2 and mGluR3): inhibit adenylyl cyclase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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