Thermo Fisher Scientific PNR Polyclonal Antibody
Human PNR 단백질을 검출하는 Rabbit Polyclonal Antibody로, IHC(P) 적용 가능. 1 mg/mL 농도의 액상 제품이며, 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: Tested at 7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from near N-terminus of human NR2E3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2200017 |
Product Specific Information
PA1-20600 detects PNR in Human samples.
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It plays a role in determining photoreceptor phenotype during human retinogenesis.
In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration.
A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte.
Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina.
ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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