Thermo Fisher Scientific MESP2 Monoclonal Antibody (1C8)

Thermo Fisher Scientific MESP2 Monoclonal Antibody (1C8)

Applications and Tested Dilution

• Immunocytochemistry (ICC/IF): 10 µg/mL
• ELISA: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
AQSPPPQSLL GHDHWIFAQG WGWAGHWDST SPASSSDSSG SCPCDGARGL PQPQPPSCSS RAAEAAATTP RRARTGPAGG QRQSASEREK LRMRTLARAL HELRRFLPPS LAPAGQSLTK IETL

Target Information

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways.
It is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites.
This gene also contributes to the formation of epithelial somitic mesoderm and cardiac mesoderm.
Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.