Thermo Fisher Scientific SLC15A1 Polyclonal Antibody
SLC15A1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer 보존. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC15A1 (Accession P46059), corresponding to amino acid residues K224–I274 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851166 |
Product Specific Information
Antibody detects endogenous levels of total SLC15A1.
Target Information
In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins.
PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues.
Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential.
PEPT1 is a 708 amino acid protein containing 12 putative membrane-spanning domains and is expressed in Caco-2 cells.
It plays important roles in nutritional and pharmacological therapies.
The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, responsible for absorption of small peptides, beta-lactam antibiotics, and other peptide-like drugs from the tubular filtrate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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