Thermo Fisher Scientific DECR2 Polyclonal Antibody
DECR2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드 항원을 기반으로 제작. 액상 형태, 1 mg/mL 농도, PBS 버퍼(50% 글리세롤) 보존. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DECR2 (Accession Q9NUI1), corresponding to amino acid residues L192–K242 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851173 |
Product Specific Information
Antibody detects endogenous levels of total DECR2.
Target Information
DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily.
Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
DECR2 also shows catalytic activity toward 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short/medium-chain 2,4-dienoyl-CoAs, indicating it is not a rate-limiting enzyme in docosahexaenoic acid degradation in the peroxisome.
DECR2 is expressed as three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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