Thermo Fisher Scientific CELSR1 Polyclonal Antibody
CELSR1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 15–20 µg/mL 농도로 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS에 0.1% sodium azide가 포함되어 있으며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 15–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from 1st extracellular domain of human CELSR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550801 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Elephant, Panda (100%)
Gibbon, Mouse, Hamster, Bovine, Dog, Horse (93%)
Rabbit (87%)
Platypus (80%)
Target Information
CELSR1 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic type cadherins, a subpopulation that does not interact with catenins. These cadherins are located at the plasma membrane and contain nine cadherin domains, seven EGF-like repeats, and two laminin A G-type repeats in their ectodomain. They also possess seven transmembrane domains, a unique characteristic of this subfamily.
It is proposed that these proteins function as receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and EGF-like domains involved in cell adhesion and receptor-ligand interactions. CELSR1 is a developmentally regulated, neural-specific gene that may play a role in early embryogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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