Thermo Fisher Scientific DDX11 Polyclonal Antibody
인간 DDX11 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.4 mg/mL 농도의 액상 형태로 제공됩니다. RNA 헬리케이스 기능 연구 및 세포 분열 관련 기전 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DDX11. Recombinant protein control fragment (Product # RP-103587) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640459 |
Product Specific Information
Immunogen sequence:
KREEEARLLE TGTGPLHDEK DESLCLSSSC EGAAGTPRPA GEPAWVTQFV QKKEERDLV
Highest antigen sequence identity to orthologs:
- Mouse: 64%
- Rat: 31%
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are involved in various cellular processes that alter RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Some members of this family are associated with embryogenesis, spermatogenesis, and cell growth and division.
DDX11 encodes a DEAD box protein with ATPase and DNA helicase activities. It is a homolog of the yeast CHL1 gene and may function to maintain chromosome transmission fidelity and genome stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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