Thermo Fisher Scientific PSMA8 Polyclonal Antibody
Rabbit polyclonal antibody against human PSMA8. Validated for Western blot at 1.0 µg/mL. Recognizes multiple species with high homology. Suitable for research on spermatogenesis and proteasome function. Supplied as liquid, 0.5 mg/mL, stored at -20°C.
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PSMA8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689693 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.
Target Information
Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively in the exchange of histones during spermatogenesis.
The proteasome is a protein complex that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I, and the progression of meiosis I during spermatogenesis.
Localizes to the synaptonemal complex, a "zipper"-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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