Thermo Fisher Scientific LILRB2 Polyclonal Antibody
인간, 마우스, 랫트에서 반응하는 LILRB2 폴리클로날 항체. Western blot 및 IHC(파라핀) 적용 가능. 친화 크로마토그래피로 정제된 1 mg/mL 액상 형태. PBS(glycerol 포함)에 저장하며 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LILRB2 (Accession Q8N423), corresponding to amino acid residues N401–P451 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853245 |
Product Specific Information
Antibody detects endogenous levels of total LILRB2.
Target Information
LILRB2 (ILT4) gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located at chromosomal region 19q13.4.
This protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
LILRB2 is expressed on immune cells, binds MHC class I molecules on antigen-presenting cells, and transduces inhibitory signals that regulate immune response activation. It plays a role in controlling inflammation and cytotoxicity to limit autoreactivity. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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