Thermo Fisher Scientific SAP18 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SAP18 protein. Validated for IHC(P) and ICC/IF applications. Antigen affinity purified and supplied in PBS with glycerol. Suitable for research on histone acetylation and gene expression regulation.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SAP18 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SAP18. Recombinant protein control fragment (Product # RP-89364) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646939 |
Product Specific Information
Immunogen sequence:
VTQEEIKKEP EKPIDREKTC PLLLRVFTTN NGRHHRMDEF SRGNVPSSEL QIYTWMDATL KELTSLVKEV YPEARKKGTH FNFAIVFTDV KRPGYRVKEI GSTMSGRKGT DDSMTLQSQK FQIGDYLDIA ITPPNRAPP
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
SAP18 is involved in histone acetylation, a key process in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.