Thermo Fisher Scientific LOXL2 Monoclonal Antibody (OTI2A7), TrueMAB
LOXL2 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot에 최적화되어 있습니다. 사람 단백질에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼에 보존되어 있으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 152–450 of human LOXL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The LOXL2 gene encodes a member of the lysyl oxidase family, which plays an essential role in connective tissue biogenesis. It encodes an extracellular copper-dependent amine oxidase that catalyzes the initial step in collagen and elastin crosslink formation.
The C-terminus contains a conserved sequence sufficient for amine oxidase activity, while the N-terminus may contribute to developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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