Thermo Fisher Scientific IL24 Polyclonal Antibody
IL24 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. Western blot 및 IHC(Paraffin) 응용에 적합하며, 비결합형 액상 형태로 제공됩니다. IL-24 관련 신호전달 연구 및 암세포 성장 억제 기전 연구에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 142–206 of IL24 (Uniprot ID: Q13007) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11151846 |
Product Specific Information
- Recommended positive control: A431
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (MDA-7), encodes a secreted protein homologous to the interleukin 10 (IL-10) family of cytokines.
Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds to heterodimeric receptors IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating JAK/STAT signaling pathways.
MDA-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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