Thermo Fisher Scientific Saccharomyces cerevisiae ZIP1 Polyclonal Antibody
Saccharomyces cerevisiae ZIP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 고순도 Protein G 정제 및 높은 농도(2.95 mg/mL)로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Saccharomyces cerevisiae ZIP1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 (1–227 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.95 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902214 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters.
Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation.
ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer.
Studies show that overexpression of ZIP1 and increased intracellular zinc in PC-3 cells inhibit NF-kappa-B, leading to down-regulation of antiapoptotic proteins Bcl-2, Bcl-XL, and XIAP, thereby reducing the malignant potential of prostate cancer cells in vitro and in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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