Thermo Fisher Scientific Clostridium botulinum Toxin F Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Clostridium botulinum Botulinum neurotoxin type F protein (1-436aa)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.5 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2902217

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 58-Gln-/-Lys-59 bond of synaptobrevins-1 and -2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.