Thermo Fisher Scientific PGAM2 Polyclonal Antibody
Thermo Fisher Scientific의 PGAM2 Polyclonal Antibody는 인간 및 설치류 시료에 반응하며, Western blot과 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 근육 특이적 PGAM2 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Bacteria, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human PGAM2 recombinant protein (UniProt ID: P15259-1, antigen range: 1–253 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155851 |
Product Specific Information
- Recommended positive controls: H1299, HeLa, rat muscle
- Predicted reactivity: Mouse (92%), Rat (93%), Zebrafish (86%), Xenopus laevis (86%), Pig (96%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphoglycerate mutase (PGAM) catalyzes the reversible conversion of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. PGAM is a dimeric enzyme composed of different isozymes depending on tissue type: muscle (MM), brain (BB), and hybrid (MB) forms.
PGAM2 encodes the muscle-specific subunit of PGAM. Mutations in this gene are associated with muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease X.
Safety and Compliance
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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