Thermo Fisher Scientific BNP/NPPB Polyclonal Antibody
BNP/NPPB 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P) 분석에 적합. 인간 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, 0.5 mg/mL 농도의 액상 형태로 제공. 심혈관 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 10 aa synthetic peptide derived from internal sequence of human BNP protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Positive control: Recombinant BNP protein
- Cellular location: Cytoplasmic, secreted
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events, one intracellularly and another after secretion into the bloodstream. Its biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and regulation of cardiovascular homeostasis. Elevated levels in the blood are indicative of heart failure. Mutations in this gene have been linked to postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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