Thermo Fisher Scientific VRK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 269-508 of human VRK2 (NP_0062872) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VRK2,uniProtId:Q86Y07-1,ncbiNodeId:9606,antigenRange:269-508,antigenLength:508,antigenImageFileName:PA5-88440_VRK2_Q86Y07-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88440_VRK2_Q86Y07-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.71 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804915

Product Specific Information

Immunogen sequence: DELPQSVLKW APSGSSCCEI AQFLVCAHSL AYDEKPNYQA LKKILNPHGI PLGPLDFSTK GQSINVHTPN SQKVDSQKAA TKQVNKAHNR LIEKKVHSER SAESCATWKV QKEEKLIGLM NNEAAQESTR RRQKYQESQE PLNEVNSFPQ KISYTQFPNS FYEPHQDFTS PDIFKKSRSP SWYKYTSTVS TGITDLESST GLWPTISQFT LSEETNADVY YYRIIIPVLL MLVFLALFFL; Positive Samples: LO2; Cellular Location: Cytoplasm, Endoplasmic reticulum membrane, Mitochondrion membrane, Nucleus, Single-pass type IV membrane protein

Target Information

VRK2 serine/threonine kinases vaccinia related kinase 2 is a member of the vaccinia-related kinase (VRK) family of kinases. VRK2 is widely expressed in human tissues and highly expressed in actively dividing cells, such as those in testis, leukocytes, fetal liver and carcinomas. VRK2 can be used to phosphorylate casein and itself undergoes autophosphorylation. VRK2 interacts specifically with Epstein-Barr virus BHRF1, a homologue of Bcl-2, and this interaction is involved in protecting cells from apoptosis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.