Thermo Fisher Scientific PCPTP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-227 of human PTPRR (NP_0028402) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCPTP1,uniProtId:Q15256-1,ncbiNodeId:9606,antigenRange:22-227,antigenLength:657,antigenImageFileName:PA5-88442_PCPTP1_Q15256-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88442_PCPTP1_Q15256-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.91 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804917

Product Specific Information

Immunogen sequence: FSGNNDHFLA INQKKSGKPV FIYKHSQDIE KSLDIAPQKI YRHSYHSSSE AQVSKRHQIV NSAFPRPAYD PSLNLLAMDG QDLEVENLPI PAANVIVVTL QMDVNKLNIT LLRIFRQGVA AALGLLPQQV HINRLIGKKN SIELFVSPIN RKTGISDALP SEEVLRSLNI NVLHQSLSQF GITEVSPEKN VLQGQHEADK IWSKEG

Positive Samples: U-87MG, HT-29, Rat heart; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein, perinuclear region, perinuclear region

Target Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.