Thermo Fisher Scientific MSH6 Monoclonal Antibody (SP93)
MSH6 단백질을 인식하는 Thermo Fisher Scientific의 SP93 단클론 항체로, 인간 시료에 반응합니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합합니다. 고순도 Protein A/G 정제, 액상 형태이며 4°C에서 보관합니다.
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Thermo Fisher Scientific MSH6 Monoclonal Antibody (SP93)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| Flow Cytometry (Flow) | 1:20 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SP93 |
| Immunogen | Synthetic peptide corresponding to internal region of human MSH6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.6, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537899 |
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using a 1 mM EDTA buffer (pH 8.0) for 10 minutes, followed by cooling at room temperature for 20 minutes.
After antigen retrieval, incubate samples with primary antibody for 30 minutes at room temperature.
A suggested positive control is rectal carcinoma.
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for detecting DNA damage and may promote apoptosis in normal cells, protecting mammals from UV-induced malignant transformation and aiding in the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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