Thermo Fisher Scientific PDE1B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PDE1B. Recombinant protein control fragment (Product #RP-92038). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE1B,uniProtId:Q01064-1,ncbiNodeId:9606,antigenRange:432-534,antigenLength:536,antigenImageFileName:PA5-53817_PDE1B_Q01064-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53817_PDE1B_Q01064-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645324

Product Specific Information

Immunogen sequence: TFSVLTDVAE KSVQPLADED SKSKNQPSFQ WRQPSLDVEV GDPNPDVVSF RSTWVKRIQE NKQKWKERAA SGITNQMSID ELSPCEEEAP PSPAEDEHNQ NGN

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

Target Information

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.