Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI1C11), TrueMAB
Human MYOZ1 단백질(aa 106-299)을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. 액상 형태로 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 근육 단백질 titin 관련 연구에 적합하며 -20°C에서 안정적으로 저장 가능.
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Applications
- Western Blot (WB): Tested Dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 106–299 of human MYOZ1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. Titin acts as a scaffold for myofibrils and other muscle-associated proteins.
The MYOZ1 gene encodes a protein expressed in striated and cardiac muscle that binds to the titin Z1–Z2 domains and serves as a substrate for titin kinase. These interactions are essential for sarcomere assembly.
Mutations in MYOZ1 are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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