Thermo Fisher Scientific AP2M1 Monoclonal Antibody (4F1B2)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1:10,000

Product Specifications

Target Information

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family.
The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes.
AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use the AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC.
AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein.
At least two isoforms of AP2M1 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지: MA5-48424_AP2M1_Q96CW1-1_House_mouse.svg)
(이미지: MA5-48424_AP2M1_Q96CW1-1_House_mouse_PDP.jpeg)