Thermo Fisher Scientific AP2M1 Monoclonal Antibody (4F1B2)
AP2M1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse IgG1 단일클론 항체. Western blot 및 ELISA에 적합하며, 고순도 Protein G 정제 및 PBS 버퍼에 보존. 인간 및 비인간 영장류 반응성. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F1B2 |
| Immunogen | Purified recombinant fragment of human AP2M1 (AA: 298–435) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090604 |
Target Information
The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family.
The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes.
AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use the AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC.
AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein.
At least two isoforms of AP2M1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-48424_AP2M1_Q96CW1-1_House_mouse.svg)
(이미지: MA5-48424_AP2M1_Q96CW1-1_House_mouse_PDP.jpeg)
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