Thermo Fisher Scientific Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody (ARC2352)
Cytokeratin 6에 특이적인 재조합 토끼 단클론 항체로, Western blot, IHC(P), ELISA에 적합합니다. 인간 시료에 반응하며, HEK293 세포에서 발현되었습니다. 고순도의 액상 형태로, 안정적인 PBS 버퍼에 보관됩니다.
- 카탈로그번호
- MA538024
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2352 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 465–564 of human Cytokeratin 6 (KRT6) (P48668) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.17 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897942 |
Product Specific Information
- Positive Samples: 5637, A-431
- Immunogen sequence:
YRKLLEGEEC RLNGEGVGQV NVSVVQSTIS SGYGGASGVG SGLGLGGGSS YSYGSGLGIG GGFSSSSGRA IGGGLSSVGG GSSTIKYTTT SSSSRKSYKH
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins).
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis, in both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas and is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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