Thermo Fisher Scientific COX 5B Polyclonal Antibody
COX 5B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 높은 특이성과 재현성을 제공합니다. 단백질 A로 정제된 액상형 항체로 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human COX 5B, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytochrome c oxidase (COX) family proteins serve as the final electron donor in the respiratory chain, driving a proton gradient across the inner mitochondrial membrane and resulting in water production. The mammalian COX apoenzyme is a dimer composed of 13 subunits—some mitochondrial, some nuclear. COX5 is a heme A-containing chain that converts oxygen and hydrogen into water. Two isoforms exist: COX5a (aerobic) and COX5b (hypoxic). COX5a transcription increases under high oxygen conditions, while COX5b transcription rises under low oxygen to optimize COX apoenzyme turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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