Thermo Fisher Scientific GREM2 Polyclonal Antibody
Thermo Fisher Scientific의 GREM2 Polyclonal Antibody는 인간 GREM2 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot에 적합하며, 합성 펩타이드 면역원 기반으로 제작되었습니다. 액상 형태로 0.5 mg/mL 농도이며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GREM2 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577277 |
Product Specific Information
Peptide sequence:
MFWKLSLSLF LVAVLVKVAE ARKNRPAGAI PSPYKDGSSN NSERWQHQIKSequence homology:
Dog: 93%
Guinea Pig: 100%
Horse: 93%
Human: 100%
Mouse: 100%
Rat: 93%
Target Information
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family.
Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers.
The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.
The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.
As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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