Thermo Fisher Scientific MRPL32 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 1:200–1:500

Product Specifications

Product Specific Information

Immunogen sequence:
RRTIEVNRCR RRNPQKLIKV KNNIDVCPEC GHLKQKHVLC AYCYEKVCKE TAEIRRQIGK QEGGPFKAPT IETVVL

• Highest antigen sequence identity to orthologs:
  • Mouse: 83%
  • Rat: 84%

Target Information

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes. These MRPs are essential for mitochondrial protein synthesis.
MRP-L32 (mitochondrial ribosomal protein L32), also known as HSPC283, is a 188 amino acid protein localized in the mitochondrion as part of the 39S ribosomal subunit. It cooperates with other MRPs to mediate protein synthesis.
The gene encoding MRP-L32 is located on human chromosome 7, which contains over 1,000 genes and accounts for nearly 5% of the human genome. Mutations in genes on chromosome 7 have been associated with various disorders, including Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.