Thermo Fisher Scientific MRPL32 Polyclonal Antibody
Human MRPL32 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 미토콘드리아 리보솜 단백질 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL32. Recombinant protein control fragment (Product # RP-101180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644139 |
Product Specific Information
Immunogen sequence:
RRTIEVNRCR RRNPQKLIKV KNNIDVCPEC GHLKQKHVLC AYCYEKVCKE TAEIRRQIGK QEGGPFKAPT IETVVL
- Highest antigen sequence identity to orthologs:
- Mouse: 83%
- Rat: 84%
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes. These MRPs are essential for mitochondrial protein synthesis.
MRP-L32 (mitochondrial ribosomal protein L32), also known as HSPC283, is a 188 amino acid protein localized in the mitochondrion as part of the 39S ribosomal subunit. It cooperates with other MRPs to mediate protein synthesis.
The gene encoding MRP-L32 is located on human chromosome 7, which contains over 1,000 genes and accounts for nearly 5% of the human genome. Mutations in genes on chromosome 7 have been associated with various disorders, including Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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