Thermo Fisher Scientific CD127 Polyclonal Antibody
Human CD127 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Interleukin 7 Receptor (amino acids 173–260 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2915710 |
Target Information
CD127 (Interleukin-7 receptor, IL-7R) is a glycoprotein involved in the regulation of lymphopoiesis. The cellular response to CD127 depends on the presence of the IL7R complex, which is an alpha/gamma chain heterodimer. The gamma(c) chain, shared with the IL-2 receptor, primarily activates signal transduction, while the alpha chain determines specific signaling events through association with cytoplasmic molecules.
CD127 promotes proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4⁺ and CD8⁺ T cells. Dysfunctions in CD127 are associated with severe combined immunodeficiency and related immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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