Thermo Fisher Scientific PolD3/p66 Polyclonal Antibody
인간 POLD3(p66) 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. DNA 복제 및 수선 관련 연구용으로 사용됩니다.
- 카탈로그번호
- IHC00249x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PolD3/p66 Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 325 and 375 of Human DNA polymerase delta, subunit 3 (POLD3, UniProt ID: Q15054-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Chimpanzee, Northern white-cheeked gibbon, and Crab-eating macaque.
Target Information
DNA replication, recombination, and repair—processes essential for genomic stability—require exonucleases. In DNA replication, exonucleases process Okazaki fragments, while in DNA repair, they excise damaged DNA and correct recombinational mismatches. These functions involve DNA polymerase families (α, β, δ, and ε). DNA polymerase δ and ε are multisubunit enzymes that interact with the sliding clamp protein PCNA. DNA polymerase δ subunit 3 (POLD3, also known as p66) is a 466-amino-acid nuclear protein essential for proper DNA polymerase δ function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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