Thermo Fisher Scientific Bestrophin 2 (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody targeting extracellular Bestrophin 2. Validated for WB and IHC at 1:200 dilution. Lyophilized form with 0.8 mg/mL concentration, stored at -20°C. Recognizes mouse Bestrophin-2 amino acids 259–270; suitable for research use only.
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- PA577291
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
- Publications: [References not provided]
Immunohistochemistry (IHC)
- Tested Dilution: 1:200
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)DPAQGYKDHTLD, corresponding to amino acid residues 259–270 of mouse Bestrophin-2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735520 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate.
The Best2 gene is a member of the bestrophin gene family of anion channels.
Bestrophin genes share a similar gene structure with conserved exon-intron boundaries but distinct 3' ends.
Bestrophins are transmembrane proteins rich in aromatic residues, including an invariant arg-phe-pro motif.
Mutation in the Best2 gene is associated with vitelliform macular dystrophy.
The Best2 gene is mainly expressed in the retinal pigment epithelium and colon.
Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-77291_Bestrophin_2_Q8BGM5-1_Rabbit.svg, PA5-77291_Bestrophin_2_Q8BGM5-1_Rabbit_PDP.jpeg)
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