Thermo Fisher Scientific Bestrophin 2 (extracellular) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

-

Immunohistochemistry (IHC)

1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)DPAQGYKDHTLD, corresponding to amino acid residues 259-270 of mouse Bestrophin-2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Bestrophin 2,uniProtId:Q8BGM5-1,ncbiNodeId:10090,antigenRange:259-270,antigenLength:508,antigenImageFileName:PA5-77291_Bestrophin_2_Q8BGM5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77291_Bestrophin_2_Q8BGM5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2735520

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3` ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.