Thermo Fisher Scientific TLR10 Monoclonal Antibody (1F8F2)
TLR10 단백질을 표적으로 하는 Mouse IgG2b 단일클론 항체로 다양한 면역학적 분석(WB, IHC, ICC, Flow, ELISA)에 사용 가능. 고순도 Protein G 정제, PBS 버퍼에 0.05% sodium azide 포함. 연구용으로 병원체 인식 및 면역 활성화 연구에 적합.
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Thermo Fisher Scientific TLR10 Monoclonal Antibody (1F8F2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F8F2 |
| Immunogen | Purified recombinant fragment of human TLR10 (AA: 20–219) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091218 |
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity.
TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
They recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents and mediate cytokine production necessary for effective immunity.
TLR10 is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil.
Its exact function is not fully understood. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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