Thermo Fisher Scientific KCNJ13 Polyclonal Antibody
Thermo Fisher Scientific의 KCNJ13 Polyclonal Antibody는 인간 KCNJ13 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. WB 및 IHC에 적합하며, 합성 펩타이드(aa 200-250)를 항원으로 제작되었습니다. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 200–250 of human KCNJ13 conjugated to an immunogenic carrier protein. Target family: Kir7.1 (KCNJ13); UniProt ID: O60928-1; NCBI Node ID: 9606; Antigen range: 200–250; Antigen length: 360 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide shares 95% identity with rat and mouse sequences.
- Specificity: KCNJ13.
Target Information
Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the voltage range for channel opening shifts to more positive values.
Inward rectification is mainly due to blockage of outward current by internal magnesium.
KCNJ13 exhibits very low single-channel conductance, low sensitivity to block by external barium and cesium, and no dependence of inward rectification on internal magnesium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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