Thermo Fisher Scientific Nectin 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NECTIN1. Recombinant protein control fragment (Product #RP-90093). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Nectin 1,uniProtId:Q15223-1,ncbiNodeId:9606,antigenRange:37-165,antigenLength:517,antigenImageFileName:PA5-82938_Nectin_1_Q15223-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82938_Nectin_1_Q15223-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790094

Product Specific Information

Immunogen sequence: DSMYGFIGTD VVLHCSFANP LPSVKITQVT WQKSTNGSKQ NVAIYNPSMG VSVLAPYRER VEFLRPSFTD GTIRLSRLEL EDEGVYICEF ATFPTGNRES QLNLTVMAKP TNWIEGTQAV LRAKKGQDD

Target Information

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.