Thermo Fisher Scientific SPANXB1 Monoclonal Antibody (OTI6G2)
Thermo Fisher Scientific SPANXB1 단클론 항체(OTI6G2)는 인간 SPANXB1 단백질을 인식하는 Mouse IgG1 형 단클론 항체로, WB와 IHC(P) 실험에 적합합니다. 고순도 Affinity Chromatography로 정제되었으며, 안정적인 PBS/BSA/glycerol 버퍼에 보존됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G2 |
| Immunogen | Full length human recombinant protein of SPANXB1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725403 |
Target Information
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa.
This gene is a member of the SPANX family of cancer/testis-associated genes, located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments.
SPANXB1 maps to chromosome X in a head-to-tail orientation with SPANXB2, which appears to be a duplication of the B1 locus. SPANXB genes contain an additional 18 nt in their coding region compared to the majority of family members.
Although the protein encoded by this gene includes consensus nuclear localization signals, its major site of localization is in the cytoplasmic droplets of ejaculated spermatozoa.
This protein serves as a biochemical marker for studying unique spermatozoa structures and its role in spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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