Thermo Fisher Scientific CKII alpha` Polyclonal Antibody
Thermo Fisher Scientific의 CKII alpha Polyclonal Antibody는 인간과 생쥐 시료에서 Casein Kinase 2 alpha 2 단백질을 검출하기 위한 고품질 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- A300199A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CKII alpha` Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and the C-terminus (residue 350) of human Casein Kinase 2, alpha 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
Casein kinase II is a protein serine/threonine kinase present in all eukaryotic cells, playing fundamental roles in cellular function. The holoenzyme forms a tetramer composed of two alpha (or alpha-prime) and two beta subunits. The alpha subunit acts as the catalytic unit, while beta subunits serve regulatory roles.
CK2 phosphorylates key signaling proteins involved in tumor suppression (p53, PTEN) and tumorigenesis (myc, jun, NF-kappaB). It also modulates Wnt signaling via beta-catenin phosphorylation and PI3K/Akt pathways.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(원본 이미지 파일: A300-199A_CK2_alpha-2_P19784-1_Rabbit_PDP.jpeg)
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