Thermo Fisher Scientific AGO1/AGO2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ELISA (ELISA)

1:3,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of both EIF2C1 and EIF2C2 corresponding to human IEF2C1/2 (eukaryotic translation initiation factor 2C1 and 2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AGO1/AGO2,uniProtId:Q9UKV8-1,ncbiNodeId:9606,antigenRange:859,antigenLength:859,antigenImageFileName:PA5-40075_AGO1AGO2_Q9UKV8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-40075_AGO1AGO2_Q9UKV8-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:AGO1/AGO2,uniProtId:Q9UL18-1,ncbiNodeId:9606,antigenRange:857,antigenLength:857,antigenImageFileName:PA5-40075_AGO1AGO2_Q9UL18-1_Rabbit.svg,antigenImageFileNamePDP:PA5-40075_AGO1AGO2_Q9UL18-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2576597

Target Information

IEF2C1 and 2 are members of the Argonaute family. These proteins are involved in short-interfering-RNA-mediated gene silencing. This process is mediated by the RISC (RNA induced silencing complex), a multicomponent nuclease that is able to degrade double stranded RNAs. The mRNA degradation is triggered by the association of specific siRNAs with their homologous mRNAs. IEF2C2 has been shown to be essential for embryonic development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.