Thermo Fisher Scientific IL12RB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:50

-

Flow Cytometry (Flow)

1:25

-

Mass Spectrometry (MS)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL12RB2,uniProtId:Q99665-1,ncbiNodeId:9606,antigenRange:756-783,antigenLength:862,antigenImageFileName:PA5-24181_IL12RB2_Q99665-1_Rabbit.svg,antigenImageFileNamePDP:PA5-24181_IL12RB2_Q99665-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2541681

Target Information

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn`s disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.