Thermo Fisher Scientific IL12RB2 Polyclonal Antibody
IL12RB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, Flow cytometry에 적용 가능. Human 시료 반응성. Protein A 및 Antigen affinity chromatography로 정제. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:25 |
| Mass Spectrometry (MS) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 756–783 amino acids from the C-terminal region of human IL12RB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541681 |
Target Information
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins leads to the formation of high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling. Expression of this gene is up-regulated by interferon gamma in Th1 cells and plays a role in Th1 cell differentiation. Up-regulation of this gene is associated with several infectious diseases, such as Crohn’s disease and leprosy, contributing to inflammatory response and host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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