Thermo Fisher Scientific SIRT3 Recombinant Rabbit Monoclonal Antibody (5T9J5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5T9J5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-399 of human SIRT3 (NP_036371.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIRT3,uniProtId:Q9NTG7-1,ncbiNodeId:9606,antigenRange:300-399,antigenLength:399,antigenImageFileName:MA5-51256_SIRT3_Q9NTG7-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51256_SIRT3_Q9NTG7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093917

Product Specific Information

Immunogen sequence: QRFLLHVVDF PMADLLLILG TSLEVEPFAS LTEAVRSSVP RLLINRDLVG PLAWHPRSRD VAQLGDVVHG VESLVELLGW TEEMRDLVQR ETGKLDGPDK

Target Information

SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.