Thermo Fisher Scientific Ly-6G Recombinant Rabbit Monoclonal Antibody (6O10Y1)
Ly-6G 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 마우스 시료 분석에 최적화됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,500–1:22,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:8,000 |
| Immunocytochemistry (ICC/IF) | 1:400–1:1,600 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6O10Y1 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 27–105 of mouse Ly-6G (NP_001297367.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3092973 |
Product Specific Information
Immunogen sequence:
LECYNCIGVP PETSCNTTTC PFSDGFCVAL EIEVIVDSHR SKVKSNLCLP ICPTTLDNTE ITGNAVNVKT YCCKEDLCN
Target Information
Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21–25 kDa and is expressed by myeloid-derived cells in the bone marrow. Ly6G serves as a marker for detection of peripheral neutrophils, monocytes, and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Although the physiological role of Ly6G remains unclear, studies indicate its involvement in anti-tumor responses and suggest that Ly6G ligation may have an inhibitory effect on local immune reactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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