Thermo Fisher Scientific Ly-6G Recombinant Rabbit Monoclonal Antibody (6O10Y1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,500-1:22,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,000-1:8,000

-

Immunocytochemistry (ICC/IF)

1:400-1:1,600

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6O10Y1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 27-105 of mouse Ly-6G (NP_001297367.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ly-6G,uniProtId:P35461-1,ncbiNodeId:10090,antigenRange:27-105,antigenLength:134,antigenImageFileName:MA5-51254_Ly-6G_P35461-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51254_Ly-6G_P35461-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3092973

Product Specific Information

Immunogen sequence: LECYNCIGVP PETSCNTTTC PFSDGFCVAL EIEVIVDSHR SKVKSNLCLP ICPTTLDNTE ITGNAVNVKT YCCKEDLCN

Target Information

Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow. Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.