Thermo Fisher Scientific OASL Polyclonal Antibody
OASL 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 최적화됨. Human에 반응하며 농도는 0.59 mg/mL. 항원 친화 크로마토그래피로 정제되었으며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA534873
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Recommended positive control: U87-MG
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 231–470 of OASL (Uniprot ID: Q15646) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552225 |
Product Specific Information
- Predicted reactivity: Chimpanzee (97%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a conserved N-terminal domain with other OASs, while the C-terminal region contains two ubiquitin-like domains. p59OASL is expressed in most tissues, with highest levels in hematopoietic tissues, colon, and stomach.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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