Thermo Fisher Scientific CaMKII gamma Polyclonal Antibody
Rabbit polyclonal antibody against CaMKII gamma for Western blot applications. Reacts with human and mouse samples. Affinity purified and supplied as a liquid at 1 mg/mL. Ideal for neuronal and muscle signaling studies. For research use only.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of Human CaMKII gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546265 |
Product Specific Information
- Recommended positive controls: HepG2, mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation. Involved in dendritic spine and synapse formation, neuronal plasticity, and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. Plays a structural role in actin cytoskeleton reorganization during neuronal plasticity. Required for proper targeting of CaMK2A, promoting dendritic spine and synapse formation and maintaining synaptic plasticity for LTP and hippocampus-dependent learning. In developing hippocampal neurons, promotes dendritic arborization; in mature neurons, promotes dendritic remodeling. Participates in modulation of skeletal muscle function in response to exercise, regulating SR Ca(2+) transport and Ca(2+) release through phosphorylation of triadin and phospholamban.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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