Thermo Fisher Scientific OSGEP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fragment corresponding to a region within amino acids 140 and 335 of OSGEP (Uniprot ID#Q9NPF4) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OSGEP,uniProtId:Q9NPF4-1,ncbiNodeId:9606,antigenRange:140-335,antigenLength:335,antigenImageFileName:PA5-21697_OSGEP_Q9NPF4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-21697_OSGEP_Q9NPF4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11157216

Product Specific Information

Recommended positive controls: Molt-4, Raji.

Predicted reactivity: Mouse (92%), Rat (95%), Zebrafish (85%), Xenopus laevis (85%), Rhesus Monkey (99%), Bovine (96%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.