Thermo Fisher Scientific OSGEP Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: Molt-4, Raji
• Predicted reactivity: Mouse (92%), Rat (95%), Zebrafish (85%), Xenopus laevis (85%), Rhesus Monkey (99%), Bovine (96%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that belongs to the peptidase M22 family.
It specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but does not cleave desialylated glycoproteins, unglycosylated proteins, or glycoproteins that are only N-glycosylated.
Although ubiquitously expressed at low levels, highest expression is observed in liver, skeletal muscle, and kidney.
OSGEPL1 (Qri7) is a 414 amino acid protein of the KAE1/YgjD family and exists as three alternatively spliced isoforms.
In tRNAs with codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.