Thermo Fisher Scientific FIGNL1 Polyclonal Antibody
Human FIGNL1 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 액상 형태로 4°C 또는 -20°C 보관 가능.
- 카탈로그번호
- PA563140
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FIGNL1 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FIGNL1 (Product #RP-92719) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641636 |
Product Specific Information
Immunogen sequence:
RLYIPLPEAS ARKQIVINLM SKEQCCLSEE EIEQIVQQSD AFSGADMTQL CREASLGPIR SLQTADIATI TPDQVRPIAY IDFENAFRTV RPSVSPK
- Highest antigen sequence identity to orthologs:
- Mouse: 88%
- Rat: 91%
Target Information
The mammalian Phospholipase Cg (PLCg) family includes two closely related proteins, PLCg1 and PLCg2. These isozymes share a core structure and possess a unique array of domains, including an additional PH domain, two SH2 domains, and one SH3 domain.
Upon stimulation by extracellular signals such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to generate the second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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