Thermo Fisher Scientific ABCB8 Polyclonal Antibody
ABCB8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 ELISA에 사용 가능. 인간, 마우스, 랫트에서 교차 반응 가능성 있음. 미토콘드리아 내막 단백질 연구에 적합. -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250–1:500 |
| ELISA | 1:20,000–1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human ABCB8. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 80 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis suggests cross-reactivity with ABCB8 from human, mouse, and rat based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. The antibody detects ABCB8 in cell lysates.
Target Information
This nuclear gene encodes a multi-pass membrane protein targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria.
Loss of function of the related gene in mouse results in disruption of iron homeostasis between the mitochondria and cytosol.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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