Thermo Fisher Scientific GP130 (extracellular) Polyclonal Antibody
GP130 단백질의 세포외 영역을 인식하는 Rabbit Polyclonal 항체. Western blot 및 Flow cytometry에 사용 가능. 동결건조 형태로 제공되며, -20°C에서 보관. 다양한 사이토카인 수용체 복합체 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:400
- View 1 publication
Flow Cytometry (Flow)
- Tested Dilution: –
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)DTLYMVHMAAYTEEG, corresponding to amino acid residues 584–598 of rat GP130 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2735869 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM).
This protein functions as a part of the cytokine receptor complex, and its activation depends on cytokine binding to their receptors.
vIL6, encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the IL6 receptor (IL6R) and directly activate this protein.
Knockout studies in mice suggest a critical role in regulating myocyte apoptosis.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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