Thermo Fisher Scientific GPR172A Polyclonal Antibody
Western blot, IHC, ICC, ELISA에 적합한 GPR172A 폴리클로날 항체. 사람, 생쥐, 랫트 반응성. Rabbit IgG 기반, Protein A 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GPR172A (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a membrane protein belonging to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption as it cannot be synthesized by the body. Riboflavin is converted to coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which act as intermediaries in many cellular metabolic reactions.
Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members, this gene shows higher expression in brain tissue than in the small intestine. Alternative splicing results in multiple transcript variants encoding the same protein. Mutations in this gene are associated with Brown-Vialetto-Van Laere syndrome 2, an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
[Provided by RefSeq, Jul 2012]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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