Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (2G5)

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:10–1:25
• Publications: -

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent
• Publications: -

Product Specifications

Additional Formats

• FITC 형식 보기
• 커스텀 컨주게이션 요청

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Mouse anti-Mouse MHC Class I antibody, clone 2G5 recognizes a monomorphic epitope present on murine MHC class I molecules, expressed at varying levels on most nucleated cells.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with beta2 microglobulin.
They carry foreign determinants essential for immune recognition by cytotoxic T cells, contributing to antiviral and antitumor defense.
Human HLA-class I antigens include HLA-A, HLA-B, and HLA-C molecules.

HLA and MHC antibodies play a significant role in immunopeptidomics, aiding in the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.