Thermo Fisher Scientific PDX1 Monoclonal Antibody (2G12)
PDX1 단백질을 인식하는 Mouse monoclonal antibody(클론 2G12). Western blot, Flow cytometry, ELISA에 적합하며, 인간 시료에 반응. Protein G 정제, 1 mg/mL 농도, PBS에 0.05% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G12 |
| Immunogen | Purified recombinant fragment of human PDX1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898505 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in early pancreatic development and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene can cause pancreatic agenesis, leading to early-onset insulin-dependent diabetes mellitus (NIDDM) and maturity-onset diabetes of the young type 4 (MODY4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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