Thermo Fisher Scientific MAP2 Polyclonal Antibody
MAP2 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot과 면역조직화학 등 다양한 응용에 적합하며, 신경세포 구조 연구에 유용합니다. 액상 형태로 PBS에 보존되며 4°C에서 장기 보관 가능합니다.
- 카탈로그번호
- PA110005
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific MAP2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:20,000–1:50,000 | View 2 publications |
| Immunohistochemistry (IHC) | 1:5,000–1:10,000 | View 5 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:5,000–1:10,000 | View 12 publications |
| in situ PLA (PLA) | – | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Pig, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mix of recombinant human constructs of projection domain sequences, amino acids 235–1588 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076848 |
Product Specific Information
PA1-10005 was raised against recombinant constructs of the entire human projection domain and recognizes only the high molecular MAP2 forms, MAP2A and MAP2B.
For long-term storage, store at 4°C.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2A & MAP2B) and a low molecular weight form. The expression of MAP2 is developmentally regulated, and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis. In rat and mouse, MAP2 is neuron-specific and enriched in dendrites, playing a role in determining and stabilizing dendritic shape during neuron development.
MAP2 is useful for studies of neuron structure in normal and malignant brain tissue, as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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