Thermo Fisher Scientific MAP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:20,000-1:50,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

1:5,000-1:10,000

View 5 publications 5 publications

Immunohistochemistry (Frozen) (IHC (F))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:5,000-1:10,000

View 12 publications 12 publications

in situ PLA (PLA)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Mix of recombinant human constructs of projection domain sequences, amino acids 235-1588. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAP2,uniProtId:P11137-1,ncbiNodeId:9606,antigenRange:235-1588,antigenLength:1827,antigenImageFileName:PA1-10005_MAP2_P11137-1_Chicken.svg,antigenImageFileNamePDP:PA1-10005_MAP2_P11137-1_Chicken_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1076848

Product Specific Information

PA1-10005 was raised against recombinant constructs of the entire human projection domain, and so recognizes only the high molecular MAP2 forms, MAP2A and MAP2B.| For long term storage, store at 4°C.

Target Information

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer`s Disease (AD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.